Enzymatic oxidation and hydrolysis of glutathione by different tissues.

نویسندگان

  • A J ZIEGENHAGEN
  • S R AMES
  • C A ELVEHJEM
چکیده

The enzymatic oxidation of reduced glutathione through a cytochrome c-linked system by a cell-free preparation of mouse kidney has been reported previously (1). Neubeck and Smythe (2) have reported the use of guinea pig liver to hydrolyze glutathione enzymatically with the liberation of cysteine; this system has been reviewed recently by Smythe (3). In this contribution the relative rates of enzymatic hydrolysis and oxidation of glutathione are investigated and the activities of cytochrome oxidase and the glutathione oxidase system are compared in several tissues of mouse and guinea pig.

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عنوان ژورنال:
  • The Journal of biological chemistry

دوره 167 1  شماره 

صفحات  -

تاریخ انتشار 1947